← Pharma & APIs
Critical node· Pharma & APIs · Critical anchor
Chromatography resins (Protein A)
Marlborough, United States42.35°N 71.55°W
computed criticality17/100
reading
Antibody-purifying Protein A resins are held by very few suppliers (Cytiva/Danaher ~35%, Merck ~16%, Repligen ~14%)
2024Fault line
Purifying a therapeutic antibody runs through Protein A chromatography resins, a scarce and costly consumable supplied by a handful of players. A silent bottleneck of all biologics production.
Actors
Cytiva
Repligen
Merck Millipore
Purolite
Sources